Facilities and expertise

Molecular neurobiology, genetics, morphology, cell biology, drug research and biochemistry tools.
Gene overexpression and shRNA silencing vector technology.
Mouse stem cell, primary retina tissue and normal cell culture.
Gene knock-out and knock-in technology using Cre/LoxP and FLP/FRT.
Transgenic DI and DMII facilities.
AAV and lentiviral gene therapy.
Oligonucleotide micro array technology (Agilent).
Electron microscopy.
Confocal laser scanning microscopy (Zeiss LSM510).

Scanning Laser Ophthalmoscope (SLO; HRA-2).

Undergraduate Projects

Undergraduate students in the life sciences may inform for possibilities to do collaborative projects in the lab (minimum of 6 months).

Jan Wijnholds is funded by

Current Funding

2011-2015 Blindness Funds (Rotterdamse Vereniging Blindenbelangen, St. Blindenhulp, Uitzicht: Algemene Nederlandse Vereniging ter Voorkoming van Blindheid, Landelijke Stichting voor Blinden en Slechtzienden, St. Blindenpenning, Macula Degeneratie Fonds, St. Winckel-Sweep, Gelderse Blinden Stichting)

2012-2014 Blindness Funds (Rotterdamse Vereniging Blindenbelangen, St. Blindenhulp)

2011-2014 Foundation Fighting Blindness USA grant

2013-2014 Foundation Fighting Blindness USA grant

2013-2014 ZonMw Gene Therapy program grant (experimental phase II)

2006-.... Netherlands Institute for Neuroscience

 

Pending Funding 

2014-2016 ZonMw Gene Therapy program grant (experimental phase III - clinical phase I)
 

Previous Funding

1990 EMBO 3-months short term Graduate fellowship
1991 EMBO 3-months short term Postdoctoral fellowship
1992-1995 Max-Planck-Society Postdoctoral Fellowship
2000-2006 KWF grant
2000-2005 Netherlands Ophthalmic Research Institute
2002-2005 van Gogh
exchange program grant
2002-2005 EC Research & Technological Development grant
2005 Blindness Funds (Rotterdamse Vereniging Blindenbelangen, Stichting OOG)
2002-2006 ZonMW TOP grant

2004-2008 Blindness Funds (Landelijke Stichting voor Blinden en Slechtzienden, Rotterdamse Vereniging Blindenbelangen, St. OOG, Algemene Nederlandse Vereniging ter voorkoming van blindheid)

2008-2009 Blindness Funds (Wendy Aartsen: Algemene Nederlandse Vereniging ter voorkoming van Blindheid, Rotterdamse Vereniging Blindenbelangen, Gelderse Blindenstichting, St. Blindenhulp, Landelijke Stichting voor Blinden en Slechtzienden)

2006-2009 ZonMw Gene Therapy program grant (experimental phase I)

2008-2011 Blindness Funds (Rotterdamse Vereniging Blindenbelangen, St. Oogfonds Nederland, St. Blindenhulp, Landelijke Stichting voor Blinden en Slechtzienden, St. Retina Nederland Fonds)

2008-2012 EC Research & Technological Development program grant

2009-2012 Blindness Funds (St. Blindenhulp, Algemene Nederlandse Vereniging ter Voorkoming van Blindheid)

Text/HTML

Wild type VEGF staining

Crb1 Knock-out VEGF staining