Central theme in this group is the understanding of ocular signal transduction as it relies on the optical parts of the eye and retina. The optical signal transduction is characterized by the retinal point-spread-function. The transparency of the relevant biological components is a critical factor. How transparency is achieved and how defects can be characterized are important research questions of this program. Normal as well as pathological conditions, including surgical (LASIK, PRK) and transplantation effects are investigated. We have specialized in straylight at the retina (Straylight introduction, PDF 2.3 MB). The work has led to an instrument for the practical clinical assessment of straylight (glare sensitivity) called C-Quant, manufactured by the German firm Oculus.