The aim of my PhD-project is to clarify the role of the horizontal cell feedback circuitry in information coding in the vertebrate retina. I use the zebrafish retina for my experiments. I will use naturalistic stimuli to investigate the coding of information at the photoreceptor-horizontal cell level. Naturalistic stimuli are used because these are the stimuli the visual system is optimized for and they will allow us to study the physiological properties of the neural network that are relevant in natural environments. The final goal is to obtain a quantitative understanding of the signal coding schemes in the outer retina.
Techniques used:
- Patch-clamp recordings, both whole-cell and perforated-patch
- Intracellular recordings
- Biophysical models