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Hypothalamic Integration Mechanisms - Andries Kalsbeek

The research of the HYP group is focused on those hypothalamic systems that control metabolism, circulation and the immune system. To unravel the mechanisms of hypothalamic integration we study the hypothalamic biological clock and how it enforces its molecular rhythms onto daily physiology and behaviour.

Hypothalamic neural networks in control of glucose homeostasis

 Thesis defence Chun-Xia Yi

 

 

28 January 2010, 10.00

 

Promotores:                 prof.dr. E. Fliers and prof.dr. R.M. Buijs.

Co-promotores:           dr. A. Kalsbeek and dr. M.J.M. Serlie. 

Rubicon grant from NWO for Chun-Xia Yi

The aim of the Rubicon programme is to encourage talented researchers at Dutch universities and research institutes run by KNAW and NWO to dedicate themselves to a career in postdoctoral research. Rubicon offers researchers who have completed their doctorates in the past year the chance to gain experience at a top research institution outside the Netherlands (maximum of two years). Chun-Xia Yi will work for 24 months at the Genome Research Institute & Obesity Research Center, Department of Medicine, University of Cincinnati (USA). Abstract

Hypothalamic News and Views (Dutch)

Latest publications

 C.X. Yi, M.J. Serlie, M.T. Ackermans, E. Foppen, R.M. Buijs, H.P. Sauerwein, E. Fliers, A. Kalsbeek - A major role for perifornical orexin neurons in the control of glucose metabolism in rats. Diabetes. 2009 Jul 10. pdf

 

L.P. Klieverik, S. Janssen, A. van Riel, E. Foppen, P.H. Bisschop, M. Serlie, A. Boelen, M.T. Ackermans, H.P. Sauerwein, E. Fliers & A. Kalsbeek – Thyroid hormone modulates glucose production via a sympathetic pathway from the hypothalamic paraventricular nucleus to the liver. PNAS 106(2009)5966-5971. pdf

 

A. Alkemade - Central and peripheral effects of Thyroid hormone signaling in the control of energy metabolism. J Neuroendocrinol. 2009 pdf

 

E. Fliers, L.P. Klieverik, A. Kalsbeek - Novel neural pathways for metabolic effects of thyroid hormone. Trends Endocrinol Metab. 2009 pdf