Selected publications

2011

 

Luigjes J, van den Brink W, Feenstra M, van den Munckhof P, Schuurman PR, Schippers R, Mazaheri A, De Vries TJ, Denys D. Deep brain stimulation in addiction: a review of potential brain targets. Mol Psychiatry. 2011 Sep 20. [Epub ahead of print]

 

Vedam-Mai V, van Battum EY, Kamphuis W, Feenstra MG, Denys D, Reynolds BA,Okun MS, Hol EM. Deep brain stimulation and the role of astrocytes. Mol Psychiatry. 2011 May 31. [Epub ahead of print]

 

van Dijk A, Mason O, Klompmakers AA, Feenstra MG, Denys D. Unilateral deep brain stimulation in the nucleus accumbens core does not affect local monoamine release. J Neurosci Methods. 2011 May 5. [Epub ahead of print]

 

Klomp A, Tremoleda JL, Wylezinska M, Nederveen AJ, Feenstra M, Gsell W,Reneman L. Lasting effects of chronic fluoxetine treatment on the late developing rat brain: Age-dependent changes in the serotonergic neurotransmitter system assessed by pharmacological MRI. Neuroimage. 2011 Aug 4. [Epub ahead of print]

 

Cohen MX, Bour L, Mantione M, Figee M, Vink M, Tijssen MA, Rootselaar AF, Munckhof PV, Richard Schuurman P, Denys D. Top-down-directed synchrony from medial frontal cortex to nucleus accumbens during reward anticipation. Hum Brain Mapp. 2011 [Epub ahead of print]

  

Figee M, Vink M, de Geus F, Vulink N, Veltman DJ, Westenberg H, Denys D. Dysfunctional reward circuitry in obsessive-compulsive disorder. Biol Psychiatry. 2011 69(9):867-74.

 

2010

 

Denys D, Mantione M, Figee M, van den Munckhof P, Koerselman F, Westenberg H, Bosch A, Schuurman R. Deep brain stimulation of the nucleus accumbens for treatment-refractory obsessive-compulsive disorder. Arch Gen Psychiatry. 2010 67(10):1061-8.

 

Mantione M, van de Brink W, Schuurman PR, Denys D. Smoking Cessation and Weight Loss After Chronic Deep Brain Stimulation of the Nucleus Accumbens: Therapeutic and Research Implications: Case Report. Neurosurgery. 66(1):E218.

 

Feenstra MG, van der Plasse G. Tryptophan depletion and serotonin release - a critical reappraisal. In: Handbook of the behavioural neurobiology of serotonin. Eds C.P.Muller, B.Jacobs. Academic Press, 249-258.

 

van Dijk A, Klompmakers A, Denys D. The serotonergic system in obsessive compulsive disorders  In: Handbook of the behavioural neurobiology of serotonin. Eds C.P.Muller, B.Jacobs. Academic Press, 547-563.

 

Kas MJ, Gelegen C, van Nieuwerburgh F, Westenberg HG, Deforce D, Denys D. Compulsivity in mouse strains homologous with chromosomes 7p and 15q linked to obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet. 2009 153B(1):252-9.


2009


Denys D, Mantione M. Deep brain stimulation in obsessive-compulsive disorder. Prog Brain Res. 2009;175:419-27.


van Duuren E, van der Plasse G, Lankelma J, Joosten RN, Feenstra MG, Pennartz CM. Single-cell and population coding of expected reward probability in the orbitofrontal cortex of the rat. J Neurosci. 2009 Jul 15;29(28):8965-76.


Valencia-Alfonso CE, Verhaal J, Güntürkün O. Ascending and descending mechanisms of visual lateralization in pigeons. Philos Trans R Soc Lond B Biol Sci. 2009 Apr 12;364(1519):955-63.


2008


Vulink NC, Rosenberg A, Plooij JM, Koole R, Bergé SJ, Denys D. Body dysmorphic disorder screening in maxillofacial outpatients presenting for orthognathic surgery. Int J Oral Maxillofac Surg. 2008 Nov;37(11):985-91.


van der Plasse G, La Fors SS, Meerkerk DT, Joosten RN, Uylings HB, Feenstra MG. Medial prefrontal serotonin in the rat is involved in goal-directed behaviour when affect guides decision making. Psychopharmacology (Berl). 2007 Dec;195(3):435-49.


Stuber GD, Klanker M, de Ridder B, Bowers MS, Joosten RN, Feenstra MG, Bonci A. Reward-predictive cues enhance excitatory synaptic strength onto midbrain dopamine neurons. Science. 2008 Sep 19;321(5896):1690-2.

 

2007


Denys D. How new is the new philosophy of psychiatry? Philos Ethics Humanit Med. 2007 Oct 20;2:22.


Denys D, Van Nieuwerburgh F, Deforce D, Westenberg HG. Prediction of response to paroxetine and venlafaxine by serotonin-related genes in obsessive-compulsive disorder in a randomized, double-blind trial. J Clin Psychiatry. 2007 May;68(5):747-53.


Westenberg HG, Fineberg NA, Denys D. Neurobiology of obsessive-compulsive disorder: serotonin and beyond. CNS Spectr. 2007 Feb;12(2 Suppl 3):14-27.


Denys D, Fineberg N, Carey PD, Stein DJ. Quetiapine addition in obsessive-compulsive disorder: is treatment outcome affected by type and dose of serotonin reuptake inhibitors? Biol Psychiatry. 2007 Feb 1;61(3):412-4.


de Geus F, Denys DA, Sitskoorn MM, Westenberg HG. Attention and cognition in patients with obsessive-compulsive disorder. Psychiatry Clin Neurosci. 2007 Feb;61(1):45-53.


van der Meulen JA, Joosten RN, de Bruin JP, Feenstra MG. Dopamine and noradrenaline efflux in the medial prefrontal cortex during serial reversals and extinction of instrumental goal-directed behavior. Cereb Cortex. 2007 Jun;17(6):1444-53.


van Duuren E, van der Plasse G, van der Blom R, Joosten RN, Mulder AB, Pennartz CM, Feenstra MG. Pharmacological manipulation of neuronal ensemble activity by reverse microdialysis in freely moving rats: a comparative study of the effects of tetrodotoxin, lidocaine, and muscimol. J Pharmacol Exp Ther. 2007 Oct;323(1):61-9.


Feenstra MGP, Microdialysis of dopamine and norepinephrine during conditioning and operant behaviour. In: Handbook of Microdialysis: Methods, Applications and Perspectives (B.H.C. Westerink & Th. Cremers, Eds), Elsevier, Amsterdam, 317-350.


2006


Fineberg NA, Stein DJ, Premkumar P, Carey P, Sivakumaran T, Vythilingum B, Seedat S, Westenberg H, Denys D. Adjunctive quetiapine for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: a meta-analysis of randomized  controlled treatment trials. Int Clin Psychopharmacol. 2006 Nov;21(6):337-43.


Denys D. Pharmacotherapy of obsessive-compulsive disorder and obsessive-compulsive spectrum disorders. Psychiatr Clin North Am. 2006 Jun;29(2):553-84, xi.


Denys D, Van Nieuwerburgh F, Deforce D, Westenberg HG. Association between serotonergic candidate genes and specific phenotypes of obsessive compulsive disorder. J Affect Disord. 2006 Mar;91(1):39-44.


Vulink NC, Denys D, Bus L, Westenberg HG. Sexual pleasure in women with obsessive-compulsive disorder? J Affect Disord. 2006 Mar;91(1):19-25.


Denys D, Van Nieuwerburgh F, Deforce D, Westenberg H. Association between the dopamine D2 receptor TaqI A2 allele and low activity COMT allele with obsessive-compulsive disorder in males. Eur Neuropsychopharmacol. 2006 Aug;16(6):446-50.


Cheng J, Feenstra MG. Individual differences in dopamine efflux in nucleus accumbens shell and core during instrumental learning. Learn Mem. 2006 Mar-Apr;13(2):168-77.

 

2005


Tenneij NH, van Megen HJ, Denys DA, Westenberg HG. Behavior therapy augments response of patients with obsessive-compulsive disorder responding to drug treatment. J Clin Psychiatry. 2005 Sep;66(9):1169-75.


2004


van der Wee NJ, Stevens H, Hardeman JA, Mandl RC, Denys DA, van Megen HJ, Kahn RS, Westenberg HM. Enhanced dopamine transporter density in psychotropic-naive patients with obsessive-compulsive disorder shown by [123I]{beta}-CIT SPECT. Am J Psychiatry. 2004 Dec;161(12):2201-6.


Denys D, Zohar J, Westenberg HG. The role of dopamine in obsessive-compulsive disorder: preclinical and clinical evidence. J Clin Psychiatry. 2004;65 Suppl 14:11-7.


Denys D, de Geus F, van Megen HJ, Westenberg HG. Use of factor analysis to detect potential phenotypes in obsessive-compulsive disorder. Psychiatry Res. 2004 Oct 30;128(3):273-80.


Denys D, de Geus F, van Megen HJ, Westenberg HG. A double-blind, randomized, placebo-controlled trial of quetiapine addition in patients with obsessive-compulsive disorder refractory to serotonin reuptake inhibitors. J Clin Psychiatry. 2004 Aug;65(8):1040-8.


Denys D, Tenney N, van Megen HJ, de Geus F, Westenberg HG. Axis I and II comorbidity in a large sample of patients with obsessive-compulsive disorder. J Affect Disord. 2004 Jun;80(2-3):155-62.


Denys D, Klompmakers AA, Westenberg HG. Synergistic dopamine increase in the rat prefrontal cortex with the combination of quetiapine and fluvoxamine. Psychopharmacology (Berl). 2004 Nov;176(2):195-203.


Denys D, van der Wee N, Janssen J, De Geus F, Westenberg HG. Low level of dopaminergic D2 receptor binding in obsessive-compulsive disorder. Biol Psychiatry. 2004 May 15;55(10):1041-5.


Mingote S, de Bruin JP, Feenstra MG. Noradrenaline and dopamine efflux in the prefrontal cortex in relation to appetitive classical conditioning. J Neurosci. 2004 Mar 10;24(10):2475-80.

 

2000-2003


Cheng JJ, de Bruin JP, Feenstra MG. Dopamine efflux in nucleus accumbens shell and core in response to appetitive classical conditioning. Eur J Neurosci. 2003 Sep;18(5):1306-14.

 

Denys D, van Megen H, Westenberg H. Quetiapine addition to serotonin reuptake inhibitor treatment in patients with treatment-refractory obsessive-compulsive disorder: an open-label study. J Clin Psychiatry. 2002 Aug;63(8):700-3.


De Bruin JP, Feenstra MG, Broersen LM, Van Leeuwen M, Arens C, De Vries S, Joosten RN. Role of the prefrontal cortex of the rat in learning and decision making: effects of transient inactivation. Prog Brain Res. 2000;126:103-13.


Feenstra MG. Dopamine and noradrenaline release in the prefrontal cortex in relation to unconditioned and conditioned stress and reward. Prog Brain Res. 2000;126:133-63.

 

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