The Netherlands Institute for Neuroscience (NIN) carries out fundamental neuroscience research with special emphasis on the brain and the visual system. Our research focusses on development, plasticity and ageing and it is often linked to clinical research questions.

The scientific structure comprises three levels of biological complexity:

• genetic and molecular approaches
• cellular approaches and network function
• system approaches

The research program is carried out in 18 research groups.
In addition, the NIN includes the Netherlands Brain Bank

MacGillavry, H.D., Stam, F.J., Sassen, M.M., Kegel, L., Hendriks, W.T.J., Verhaagen, J., Smit, A.B., and Van Kesteren, R.E. NFIL3 and cAMP response element-binding protein form a transcriptional feedforward loop that controls neuronal regeneration-associated gene expression. Journal of Neuroscience 29 (2009) 15542-15550.

Van Genderen, M.M., Bijveld, M.M.C., Claassen, Y.B., Florijn, R.J., Pearring, J.N., Meire, F.M., McCall, M.A., Riemslag, F.C.C., Gregg, R.G., Bergen, A.A.B., and Kamermans, M. Mutations in TRPM1 are a common cause of complete congenital stationary night blindness. American Journal of Human Genetics 85 (2009) 730-736.   

Van der Werf, Y.D., Van der Helm, E., Schoonheim, M.M., Ridderikhoff, A., and Van Someren, E.J.W. Learning by observation requires an early sleep window. PNAS 106 (2009) 18926-18930.

Allikmets, R., Bergen, A.A.B., Dean, M., Guymer, R.H., Hageman, G.S., Klaver, C.C., Stefansson, K., Weber, B.H. and the international Age-related Macular Degeneration Genetics Consortium. Geographic atrophy in age-related macular degeneration and TLR3. New Engl J Med. 360 (2009) 2252-4. (Letter)

 
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